Laboratory Diagnosis of Glandular Fever

Laboratory diagnosis of glandular fever.

A common feature of the numerous published studies on glandular fever is the wide variation encountered in the clinical and pathological manifestations of the disease (Davidsohn, 1952). This has permitted the clinician to label a wide variety of illnesses as glandular fever even in the presence of persistently negative laboratory findings. It is, therefore, far from clear whether the diagnosis ...

A simplified method for the serological diagnosis of glandular fever.

It is well known that the simple sheep cell agglutination test of Paul and Bunnell as an aid to the diagnosis of glandular fever is subject to considerable limitations. To obtain reliable serological evidence of infection it is necessary to resort to the absorption test, which is, however, somewhat laborious. The purpose of this note is to draw attention to the fact that virtually the same info...

Glandular fever (infectious mononucleosis).

Glandular Fever: Infectious Mononucleosis

Seronegative glandular fever.

Seven sporadic cases of ;seronegative glandular fever' have been examined in detail; five of the patients were adults aged more than 30, two were children. None showed evidence of ;incomplete' or heat-labile sheep cell agglutinins, but in three very weak, though otherwise typical, glandular fever agglutinins were detected. Three of the other four showed evidence of certain infections, but these...